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Estrogen Receptor alpha 抗体 (AA 2-185) (PE)

This anti-Estrogen Receptor alpha antibody is a 小鼠 单克隆 antibody detecting Estrogen Receptor alpha in IF, FACS 和 T. Suitable for 人.
产品编号 ABIN6935636
发货至: 中国

Quick Overview for Estrogen Receptor alpha 抗体 (AA 2-185) (PE) (ABIN6935636)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Estrogen Receptor alpha antibody is conjugated to PE

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)

克隆位点

ER506
  • 抗原表位

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    AA 2-185

    特异性

    This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human Estrogen Receptor alpha protein (aa2-185)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: MCF-7 cells. Breast or Endometrial Carcinoma.

    Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100 for 30 minutes at RT),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    100 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA and 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    ESR1

    分子量

    ~67kDa

    基因ID

    2099

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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