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Cytokeratin 5 抗体 (AA 318-491)

KRT5 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal KRT5-2080 unconjugated
产品编号 ABIN6934855
发货至: 中国
  • 抗原 See all Cytokeratin 5 (KRT5) 抗体
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    抗原表位
    • 16
    • 16
    • 10
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 318-491
    适用
    • 114
    • 76
    • 49
    • 12
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 83
    • 41
    • 1
    小鼠
    克隆类型
    • 72
    • 53
    单克隆
    标记
    • 58
    • 15
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Cytokeratin 5 antibody is un-conjugated
    应用范围
    • 87
    • 51
    • 46
    • 31
    • 24
    • 17
    • 14
    • 14
    • 13
    • 8
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
    交叉反应 (详细)
    Human.
    免疫原
    Recombinant human Cytokeratin 5 (KRT5) protein fragment (around aa 318-491) (exact sequence is proprietary)
    克隆位点
    KRT5-2080
    亚型
    IgG1 kappa
    Top Product
    Discover our top product KRT5 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1:50-1:100 for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or HeLa cells. Tonsil, Esophagus, Cervix or Urinary Bladder. Basal Cell or Squamous Cell Carcinoma.

    限制
    仅限研究用
  • 缓冲液
    Tissue culture supernatant with 0.05% Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    别名
    KRT5 (KRT5 产品)
    别名
    3300001P10Rik antibody, AW146334 antibody, CK5 antibody, K5 antibody, Krt2-5 antibody, Tfip8 antibody, DDD antibody, DDD1 antibody, EBS2 antibody, KRT5A antibody, Sak57 antibody, ckii antibody, wu:fb02h09 antibody, wu:fj02d02 antibody, wu:fk78b12 antibody, zfCKII antibody, KRT75 antibody, CK-5 antibody, Keratin-5 antibody, keratin 5 antibody, Krt5 antibody, KRT5 antibody, krt5 antibody
    背景
    58 kDa Cytokeratin, CK5, Cytokeratin-5, DDD1, Epidermolysis Bullosa Simplex 2 (EBS2), Keratin 5, Keratin, Type II Cytoskeletal 5, Keratin-5, KRT5, Type-II Cytoskeletal 5, Type-II keratin Kb5,Cytokeratin 5 (KRT5) (Basal, Myoepithelial & Mesothelial Cell Marker)
    Cellular localisation: Cytoplasmic
    分子量
    58kDa
    基因ID
    3852, 433845
    UniProt
    P13647
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