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KRT77, KRT76 抗体 (PE)

适用: 人, 大鼠, 小鸡, Cow, 犬, 猴, 小鼠, 兔 FACS, IF, T 宿主: 小鼠 Monoclonal SPM115-SPM116 PE
产品编号 ABIN6933732
发货至: 中国
  • 抗原
    KRT77, KRT76
    适用
    人, 大鼠, 小鸡, Cow, 犬, 猴, 小鼠, 兔
    宿主
    • 5
    • 3
    小鼠
    克隆类型
    • 7
    • 1
    单克隆
    标记
    • 7
    • 1
    PE
    应用范围
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
    特异性
    Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
    纯化方法
    Purified by Protein A/G
    免疫原
    Human epidermal keratin
    克隆位点
    SPM115-SPM116
    亚型
    IgG1 kappa
  • 应用备注

    Positive Control: Skin, Adeno- or Squamous carcinomas.

    Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100 for 30 minutes at RT),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    100 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    KRT77, KRT76
    别名
    KRT77 & KRT76
    分子量
    67kDa (CK1), 64kDa (CK3), 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8), 56.5kDa (CK10), 50kDa (CK14), 50kDa (CK15), 48kDa (CK16), 40kDa (CK19)
    基因ID
    374454, 51350
    UniProt
    Q7Z794, Q01546
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