tau 抗体 (pSer202, pThr205) (PE)
Quick Overview for tau 抗体 (pSer202, pThr205) (PE) (ABIN6932906)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
- 
    
- 
                                            
抗原表位
 - pSer202, pThr205
 - 
                                            
特异性
 - Expressed in neurons.,Detects ~79 kDa.
 - 
                                            
交叉反应
 - 人, 小鼠
 - 
                                            
纯化方法
 - Affinity Purified
 - 
                                            
免疫原
 - Synthetic peptide of Human Phospho Tau (Ser202/Thr205)
 - 
                                            
亚型
 - IgG
 
 - 
                                            
 - 
    
 - 
    
- 
                                            
应用备注
 - 
                        
- WB (1:500)
 - ICC/IF (1:500)
 - IHC (1:500)
 - optimal dilutions for assays should be determined by the user.
 
 - 
                                            
说明
 - 
                        
A 1:500 dilution of ABIN6932906 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
 - 
                                            
限制
 - 仅限研究用
 
 - 
                                            
 - 
    
- 
                                            
状态
 - Liquid
 - 
                                            
浓度
 - 1 mg/mL
 - 
                                            
缓冲液
 - PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
 - 
                                            
储存液
 - Sodium azide
 - 
                                            
注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 - 
                                            
储存条件
 - 4 °C
 - 
                                            
储存方法
 - Conjugated antibodies should be stored at 4°C
 
 - 
                                            
 - 
    
- tau (tau Protein)
 - 
                                            
别名
 - Tau
 - 
                                            
背景
 - Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).
 - 
                                            
基因ID
 - 4137
 - 
                                            
UniProt
 - P10636
 
抗原
 -