tau 抗体 (pSer202, pThr205) (Biotin)
Quick Overview for tau 抗体 (pSer202, pThr205) (Biotin) (ABIN6932896)
抗原
See all tau 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer202, pThr205
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特异性
- Expressed in neurons.,Detects ~79 kDa.
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交叉反应
- 人, 小鼠
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide of Human Phospho Tau (Ser202/Thr205)
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亚型
- IgG
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应用备注
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- WB (1:500)
- ICC/IF (1:500)
- IHC (1:500)
- optimal dilutions for assays should be determined by the user.
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说明
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A 1:500 dilution of ABIN6932896 was sufficient for detection of Tau in 10 μg Baculovirus by dot blot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- tau (tau Protein)
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别名
- Tau
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背景
- Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3).
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基因ID
- 4137
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UniProt
- P10636
抗原
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