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CD46 抗体 (AA 251-355)

This anti-CD46 antibody is a 兔 多克隆 antibody detecting CD46 in WB, FACS, ELISA, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN687832
发货至: 中国

Quick Overview for CD46 抗体 (AA 251-355) (ABIN687832)

抗原

See all CD46 抗体
CD46

适用

  • 130
  • 36
  • 23
  • 11
  • 10
  • 3
人, 小鼠

宿主

  • 90
  • 63
  • 2
  • 1

克隆类型

  • 79
  • 77
多克隆

标记

  • 63
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is un-conjugated

应用范围

  • 92
  • 86
  • 42
  • 41
  • 38
  • 23
  • 22
  • 13
  • 13
  • 9
  • 7
  • 5
  • 4
  • 2
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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 10
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-355

    交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from Mouse CD46

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CD46

    别名

    CD46/MCP

    背景

    Synonyms: MCP, TLX, AHUS2, MIC10, TRA2.10, Membrane cofactor protein, Trophoblast leukocyte common antigen, CD46

    Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

    基因ID

    4179

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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