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CD63 抗体 (AA 101-200)

CD63 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN687742
发货至: 中国
  • 抗原 See all CD63 抗体
    CD63
    抗原表位
    • 12
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 128
    • 48
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 76
    • 62
    • 4
    • 3
    克隆类型
    • 97
    • 46
    • 2
    多克隆
    标记
    • 70
    • 12
    • 11
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This CD63 antibody is un-conjugated
    应用范围
    • 90
    • 68
    • 49
    • 43
    • 34
    • 28
    • 26
    • 19
    • 18
    • 16
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CD63
    亚型
    IgG
    Top Product
    Discover our top product CD63 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Del Pozo-Acebo, Hazas, Tomé-Carneiro, Gil-Cabrerizo, San-Cristobal, Busto, García-Ruiz, Dávalos: "Bovine Milk-Derived Exosomes as a Drug Delivery Vehicle for miRNA-Based Therapy." in: International journal of molecular sciences, Vol. 22, Issue 3, (2021) (PubMed).

    Marzesco, Flötenmeyer, Bühler, Obermüller, Staufenbiel, Jucker, Baumann: "Highly potent intracellular membrane-associated Aβ seeds." in: Scientific reports, Vol. 6, pp. 28125, (2016) (PubMed).

    Sun, Zhao, Li, Wang, Nie, Peng, Wang, Zhang, Tian, Li, Song, Wang, Xu, Tian, Zhao, Xu, Zhong, Han, Ling, Chang, Li: "Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity." in: Cell discovery, Vol. 2, pp. 16015, (2016) (PubMed).

    Son, Rahimian, Shin, Siltanen, Patel, Revzin: "Microfluidic compartments with sensing microbeads for dynamic monitoring of cytokine and exosome release from single cells." in: The Analyst, (2015) (PubMed).

  • 抗原
    CD63
    别名
    CD63/MLA1 (CD63 产品)
    别名
    C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody
    背景

    Synonyms: MLA1, ME491, LAMP-3, OMA81H, TSPAN3, CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, Tetraspanin-3, Tspan-3, CD63

    Background: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

    基因ID
    967
    UniProt
    P08962
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