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TRAP1 抗体 (AA 501-650) (FITC)

This anti-TRAP1 antibody is a 兔 多克隆 antibody detecting TRAP1 in IF (cc) 和 IF (p). Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN686654
发货至: 中国

Quick Overview for TRAP1 抗体 (AA 501-650) (FITC) (ABIN686654)

抗原

See all TRAP1 抗体
TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

适用

  • 82
  • 33
  • 19
  • 4
  • 2
  • 1
大鼠

宿主

  • 79
  • 17

克隆类型

  • 70
  • 25
多克隆

标记

  • 42
  • 7
  • 5
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TRAP1 antibody is conjugated to FITC

应用范围

  • 57
  • 28
  • 27
  • 24
  • 15
  • 12
  • 12
  • 11
  • 8
  • 4
  • 3
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-650

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HSP75

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Lettini, Sisinni, Condelli, Matassa, Simeon, Maddalena, Gemei, Lopes, Vita, Del Vecchio, Esposito, Landriscina: "TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).

  • 抗原

    TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

    别名

    Hsp75/Trap1

    背景

    Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1

    Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

    基因ID

    10131

    UniProt

    Q12931
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