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TLR3 抗体 (AA 801-905)

Name: TLR3 抗体 (AA 801-905)
SKU: ABIN686617
Availability: OutOfStock

This anti-TLR3 antibody is a 兔多克隆 antibody detecting TLR3 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 4+ publications.

Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti TLR3 Polyclonal Antibody, Unconjugated (ABIN686617) at 1:200 followed by conjugation to the secondary antibody and DAB staining (TLR3 抗体 (AA 801-905))

IHC

Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-TLR3 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (TLR3 抗体 (AA 801-905))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat kidney tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-TLR3 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (TLR3 抗体 (AA 801-905))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded rat lung tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-TLR3 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (TLR3 抗体 (AA 801-905))

IHC (p)

4 images

(4 references)

产品编号 ABIN686617

发货至: 中国

Quick Overview for TLR3 抗体 (AA 801-905) (ABIN686617)

抗原

See all TLR3 抗体

TLR3 (Toll-Like Receptor 3 (TLR3))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This TLR3 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product TLR3 Primary Antibody

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AA 801-905

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse TLR3

亚型

IgG
anti-Toll-Like Receptor 3 (TLR3) (AA 404-532) antibody
TLR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 464-647) antibody
TLR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 24-217) antibody
TLR3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F3G4 unconjugated

anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibody
TLR3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 135-297) antibody
TLR3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 55-70) antibody
TLR3 适用: 人, 猴, 山羊, 绵羊 WB, IHC, FACS, IP, IHC (p) 宿主: 小鼠 Monoclonal 40C1285-6 unconjugated

anti-Toll-Like Receptor 3 (TLR3) antibody
TLR3 适用: 小鼠 FACS, IF 宿主: 大鼠 Monoclonal 11F8 unconjugated

anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibody
TLR3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 750-800), (pTyr759) antibody
TLR3 适用: 人 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 3 (TLR3) (AA 135-150) antibody
TLR3 适用: 小鼠 WB, IHC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Zhao, Zhang, Wang, Jin, Zhou, Chen, Su: "Activation of Toll-like receptor 3 promotes pathological corneal neovascularization by enhancement of SDF-1-mediated endothelial progenitor cell recruitment." in: Experimental eye research, Vol. 178, pp. 177-185, (2019) (PubMed).

Zhu, Xu, Jiang, Wang, Geng, Wu, Hussain, Gao, Han, Li, Lan, Ning, Zhang, Holmdahl, Meng, Lu: "Pristane induces autophagy in macrophages, promoting a STAT1-IRF1-TLR3 pathway and arthritis." in: Clinical immunology (Orlando, Fla.), Vol. 175, pp. 56-68, (2016) (PubMed).

Wang, Lei, Zhang, Zhao, Fang, Lai, Han, Xiao, Wang: "Xenobiotic Pregnane X Receptor (PXR) Regulates Innate Immunity via Activation of NLRP3 Inflammasome in Vascular Endothelial Cells." in: The Journal of biological chemistry, Vol. 289, Issue 43, pp. 30075-81, (2014) (PubMed).

Zhu, Meng, Jiang, Xu, Wang, Han, Lu: "Overexpression of toll-like receptor 3 in spleen is associated with experimental arthritis in rats." in: Scandinavian journal of immunology, Vol. 76, Issue 3, pp. 263-70, (2012) (PubMed).
抗原

TLR3 (Toll-Like Receptor 3 (TLR3))

别名

TLR3

背景

Synonyms: AI957183, Toll-like receptor 3, CD283, Tlr3
Background: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response (By similarity).

基因ID

142980

UniProt

Q99MB1

途径

TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades