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JAK1 抗体 (HRP)

JAK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN686566
发货至: 中国
  • 抗原 See all JAK1 抗体
    JAK1 (Janus Kinase 1 (JAK1))
    适用
    • 102
    • 81
    • 61
    • 2
    • 2
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 82
    • 26
    • 1
    • 1
    克隆类型
    • 81
    • 29
    多克隆
    标记
    • 50
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    • 4
    • 4
    • 4
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    • 3
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    This JAK1 antibody is conjugated to HRP
    应用范围
    • 74
    • 38
    • 26
    • 16
    • 16
    • 14
    • 11
    • 11
    • 8
    • 4
    • 3
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    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human JAK1
    亚型
    IgG
    Top Product
    Discover our top product JAK1 Primary Antibody
  • 应用备注
    WB(1:100-1000), IHC-P(1:100-500)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Gentamicin sulfate
    注意事项
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    JAK1 (Janus Kinase 1 (JAK1))
    别名
    Jak1 (JAK1 产品)
    别名
    JAK1A antibody, JAK1B antibody, JTK3 antibody, AA960307 antibody, C130039L05Rik antibody, wu:fb93e10 antibody, jak1 antibody, Janus kinase 1 antibody, tyrosine-protein kinase JAK1 antibody, JAK1 antibody, Jak1 antibody, jak1 antibody, LOC100286690 antibody
    背景

    Synonyms: JAK 1, JAK 1A, JAK 1B, JAK1, JAK1A, JAK1B, Janus kinase 1 a protein tyrosine kinase, Janus kinase 1, JTK3, Tyrosine protein kinase JAK 1, Tyrosine protein kinase JAK1, JAK1_HUMAN.

    Background: Janus kinase 1 (JAK1) is a member of a new class of non-receptor protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. It is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon recpeptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.

    基因ID
    3716
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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