Claudin 1 抗体 (AA 121-211)
(1 reference)Quick Overview for Claudin 1 抗体 (AA 121-211) (ABIN686407)
抗原
See all Claudin 1 (CLDN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 121-211
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse Claudin 1
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亚型
- IgG
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anti-Claudin 1 (CLDN1) (AA 1-211) antibody
CLDN1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2E2-H5 unconjugated
anti-Claudin 1 (CLDN1) (AA 50-197) antibodyCLDN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-212) antibodyCLDN1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (C-Term) antibodyCLDN1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 185-224) antibodyCLDN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (Tyr210) antibodyCLDN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 24-161) antibodyCLDN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." in: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).
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: "Notch inhibition promotes fetal liver stem/progenitor cells differentiation into hepatocytes via the inhibition of HNF-1?." in: Cell and tissue research, Vol. 357, Issue 1, pp. 173-84, (2014) (PubMed).
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- Claudin 1 (CLDN1)
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别名
- Claudin 1
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背景
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Synonyms: AI596271, Claudin-1, Cldn1
Background: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.
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基因ID
- 12737
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UniProt
- O88551
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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