AKAP12 抗体 (AA 701-900)
Quick Overview for AKAP12 抗体 (AA 701-900) (ABIN685732)
抗原
See all AKAP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 701-900
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human of human AKAP12
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亚型
- IgG
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anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1485-1782) antibody
AKAP12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1675-1782) antibodyAKAP12 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) antibodyAKAP12 适用: 大鼠 WB 宿主: 绵羊 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1719-1782) antibodyAKAP12 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (C-Term) antibodyAKAP12 适用: 人 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 301-350) antibodyAKAP12 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 12 (AKAP12) (AA 1639-1652), (Intracellular) antibodyAKAP12 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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别名
- AKAP12/Gravin
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背景
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Synonyms: A kinase PRKA anchor protein gravin 12, A kinase Anchor Protein 12, A kinase anchor protein 250 kDa, AKAP 12, AKAP 250, AKAP250, DKFZp686M0430, DKFZp686O0331, Gercelin, Gravin, Kinase scaffold protein gravin, Myasthenia gravis autoantigen gravin, Srcs5, SSeCKS, Tsga12.
Background: Gravin (also known as A Kinase Anchor Protein 12, AKAP12) was cloned from a cDNA expression library screened with serum, from a myasthenia gravis patient. to Gravin were found in 22 out of 72 myasthemia gravis patients and absent in sera of normal individuals. This protein is a myristoylated high molecular weight cytoplasmic protein expressed in endothelial cells, cultured fibroblasts and osteosarcoma cells and highly expressed in the brain. Gravin can bind kinases like PKA and PKC by different domains of the protein and can localize these kinases to specific domains in the cell. Upon differentiation of NT2 cells to neurons (NT2 N), Gravin expression is up regulated and enriched at the inner peripheral cortex in close proximity to the plasma membrane. In differentiated cells, gravin is co-localized with PKCbII, PKCa and PKA. Decreased binding of PKCa to gravin was found after activation of PKC.
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基因ID
- 9590
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途径
- cAMP Metabolic Process
抗原
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