FLT3 抗体 (pTyr589, pTyr591)
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- 抗原 See all FLT3 抗体
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
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抗原表位
- pTyr589, pTyr591
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FLT3 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human FLT3 around the phosphorylation site of Tyr589/591
- 亚型
- IgG
- Top Product
- Discover our top product FLT3 Primary Antibody
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anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibodyFLT3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibodyFLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibodyFLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibodyFLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibodyFLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibodyFLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC
anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibodyFLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
- 别名
- FLT3 + (FLT3 产品)
- 别名
- FLT3 antibody, B230315G04 antibody, CD135 antibody, Flk-2 antibody, Flk2 antibody, Flt-3 antibody, Ly72 antibody, wmfl antibody, FLK-2 antibody, FLK2 antibody, STK1 antibody, fms related tyrosine kinase 3 antibody, FMS-like tyrosine kinase 3 antibody, fms-related tyrosine kinase 3 antibody, FLT3 antibody, Flt3 antibody
- 背景
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Synonyms: CD135 antigen, Fetal liver kinase 2, FL cytokine receptor, Flk 2, Flk2, Flt 3, Flt3, FMS like tyrosine kinase 3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, Stk 1, Stk1, Tyrosine protein kinase receptor FLT3, FLT3_HUMAN.
Background: CD135 is a tyrosine kinase receptor expressed on normal cells including CD34+ hematopoietic stem cells, myelomonocytic progenitors, primitive B cell progenitors, and thymocytes. CD135 is also expressed on malignant hematopoietic cells including AML, ALL and CML BC. CD135, also known as FMS-like tyrosine kinase 3, FLT3, STK1, and Flk2, is a growth factor receptor that binds the FLT3 ligand to promote the growth and differentiation of primitive hematopoietic cells. The intracytoplasmic domain of CD135 is modified by phosphorylation and has been shown to interact with Grb2, SOCS1, VAV1, and Shc. In humans, expression of Flt3 is restricted to subsets of CD34 positive as well as CD34 negative normal bone marrow cells. In these cells, the level of expression of Flt3 is rather low. Most of the CD34 bright Flt3+ cells co-express CD117 at high levels. They may represent early cycling, but not quiescent stem cells. Flt3+ cells in the CD34lo and CD34- populations do not co-express CD117 Molecule and may represent B lymphoid precursors.
- 基因ID
- 2322
- 途径
- RTK signaling
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