ABL1 抗体 (pTyr89)
Quick Overview for ABL1 抗体 (pTyr89) (ABIN683698)
抗原
See all ABL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr89
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Tyr89
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亚型
- IgG
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anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 490-590) antibody
ABL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr251) antibodyABL1 适用: 人 WB, IF, IHC (p), DB 宿主: 兔 Polyclonal RB7351 unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibodyABL1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr393), (pTyr412) antibodyABL1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (AA 741-769) antibodyABL1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr204) antibodyABL1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr245) antibodyABL1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) (pTyr412) antibodyABL1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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别名
- c-Abl
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背景
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Synonyms: c-Ablphospho Y89, c-Ablphospho Tyr89, p-c-AblTyr89, tyrosine-protein kinase ABL1 isoform b, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, ABL, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, p150 , Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, v abl Abelson murine leukemia viral oncogene homolog 1, v abl, ABL1_HUMAN.
Background: The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq].
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基因ID
- 25
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途径
- Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
抗原
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