MAP3K11 抗体 (AA 355-460) (Biotin)
Quick Overview for MAP3K11 抗体 (AA 355-460) (Biotin) (ABIN682575)
抗原
See all MAP3K11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 355-460
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特异性
- Due to the similarity of this protein to MLK1 2 and 4, there is a chance that this antibody will cross-react based on homology.
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MLK3
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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别名
- MLK3
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背景
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Synonyms: MLK3, PTK1, SPRK, MLK-3, MEKK11, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase, MAP3K11
Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
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分子量
- 94kDa
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基因ID
- 4296
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UniProt
- Q16584
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途径
- MAPK Pathway, Interferon-gamma Pathway
抗原
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