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Vitamin D Receptor 抗体 (AA 65-180)

This anti-Vitamin D Receptor antibody is a 兔 多克隆 antibody detecting Vitamin D Receptor in WB, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN682513
发货至: 中国

Quick Overview for Vitamin D Receptor 抗体 (AA 65-180) (ABIN682513)

抗原

See all Vitamin D Receptor (VDR) 抗体
Vitamin D Receptor (VDR)

适用

  • 96
  • 59
  • 43
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 105
  • 13
  • 1
  • 1

克隆类型

  • 96
  • 24
多克隆

标记

  • 65
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This Vitamin D Receptor antibody is un-conjugated

应用范围

  • 94
  • 34
  • 25
  • 25
  • 22
  • 13
  • 12
  • 11
  • 11
  • 10
  • 5
  • 2
  • 2
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 14
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-180

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Vitamin D Receptor

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Wu, Chen, Tian, Zhang, Bian, Cheng: "Serum 25-hydroxyvitamin D inversely associated with blood eosinophils in patients with persistent allergic rhinitis." in: Asia Pacific allergy, Vol. 7, Issue 4, pp. 213-220, (2017) (PubMed).

    Zhang, Zhou, Guo, Song, Liu: "1,25-Dihydroxyvitamin D₃ Promotes High Glucose-Induced M1 Macrophage Switching to M2 via the VDR-PPARγ Signaling Pathway." in: BioMed research international, Vol. 2015, pp. 157834, (2016) (PubMed).

    Tian, Lv, Yang, Zhang, Yu, Zhu, Xiao, Zhu: "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3028-37, (2014) (PubMed).

    Song, Guo, Zhou, Zhang: "The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats." in: Metabolism: clinical and experimental, Vol. 63, Issue 10, pp. 1324-33, (2014) (PubMed).

    Zhang, Song, Guo, Zhou: "The novel role of TRPC6 in vitamin D ameliorating podocyte injury in STZ-induced diabetic rats." in: Molecular and cellular biochemistry, (2014) (PubMed).

  • 抗原

    Vitamin D Receptor (VDR)

    别名

    Vitamin D Receptor/VDR

    物质类

    Chemical

    背景

    Synonyms: NR1I1, PPP1R163, Vitamin D3 receptor, VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

    Background: Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

    基因ID

    7421

    UniProt

    P11473

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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