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ARHGEF7 抗体 (AA 201-300)

This anti-ARHGEF7 antibody is a 兔 多克隆 antibody detecting ARHGEF7 in ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN681943
发货至: 中国

Quick Overview for ARHGEF7 抗体 (AA 201-300) (ABIN681943)

抗原

See all ARHGEF7 抗体
ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

适用

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宿主

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克隆类型

  • 50
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多克隆

标记

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This ARHGEF7 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 201-300

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ARHG7.

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

    别名

    ARHG7

    背景

    Synonyms: ARHG7_HUMAN, ARHG7, ARHGEF 7, ARHGEF7, Beta pix, betaPix, betaPix-b, betaPix-c, Cool, COOL1, P50 antibody P50BP, P85, P85COOL1, P85SPR, PAK interacting exchange factor beta, PAK3, Pak3bp, PAK3BP, PIX, PIXB, Rho guanine nucleotide exchange factor GEF 7, Rho guanine nucleotide exchange factor GEF 7b, Rho guanine nucleotide exchange factor GEF7, Rho guanine nucleotide exchange factor 7, SH3 domain containing proline rich protein, Nbla10314, KIAA0142.

    Background: ARHGEF7 is a p21-activated protein kinase (Pak)-interacting exchange factor that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. It is expressed ubiquitously in all the tissue examined and other isoforms are expressed mainly in the central nervous system. Regulated phosphorylation of ARHGEF7 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined.

    基因ID

    8874

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation
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