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LRP5 抗体 (AA 451-550)

This anti-LRP5 antibody is a 兔 多克隆 antibody detecting LRP5 in ELISA, IF (p) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN681478
发货至: 中国

Quick Overview for LRP5 抗体 (AA 451-550) (ABIN681478)

抗原

See all LRP5 抗体
LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

适用

  • 59
  • 50
  • 24
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 7
  • 2
  • 1

克隆类型

  • 71
  • 6
多克隆

标记

  • 32
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LRP5 antibody is un-conjugated

应用范围

  • 39
  • 27
  • 25
  • 19
  • 13
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 2
  • 1
ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 14
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 451-550

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LRP6

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Huang, Fantini, Merrill, Bagchi, Guzman, Raychaudhuri: "DDB2 Is a Novel Regulator of Wnt Signaling in Colon Cancer." in: Cancer research, Vol. 77, Issue 23, pp. 6562-6575, (2018) (PubMed).

  • 抗原

    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

    别名

    LRP5 + LRP6

    背景

    Synonyms: ADCAD2, C030016K15Rik, Cd, FLJ90062, FLJ90421, Low density lipoprotein receptor related protein 6, LRP6_HUMAN, Low-density lipoprotein receptor-related protein 6, low-density lipoprotein receptor-related protein 6 precursor, LRP-6, LRP-5, LR3, LRP7, Low-density lipoprotein receptor-related protein 5.

    Background: This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].

    基因ID

    4040, 4041

    途径

    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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