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HDAC6 抗体 (AA 301-400)

Name: HDAC6 抗体 (AA 301-400)
SKU: ABIN681058
Availability: OutOfStock

HDAC6 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human brain labeled with Anti-HDAC6 Polyclonal Antibody, Unconjugated (ABIN681058) at 1:200 followed by conjugation to the secondary antibody and DAB staining (HDAC6 抗体 (AA 301-400))

IHC

Paraformaldehyde-fixed, paraffin embedded rat kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with HDAC6 Polyclonal Antibody (bs-2811R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining. (HDAC6 抗体 (AA 301-400))

IHC (p)

2 images

产品编号 ABIN681058

发货至: 中国

Datasheet as PDF

抗原 See all HDAC6 抗体

HDAC6 (Histone Deacetylase 6 (HDAC6))
抗原表位
26

15

14

10

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 301-400
适用
119

39

26

8

5

4

3

3

3

2

1

1

1
人, 大鼠
宿主
106

16

1
兔
Compatible Secondaries
克隆类型
100

23
多克隆
标记
68

9

5

4

4

4

4

4

4

3

2

2

2

2

2

2

2
This HDAC6 antibody is un-conjugated
应用范围
98

41

40

26

26

25

18

14

12

9

5

5

3

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 大鼠

预测反应

Mouse,Cow,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human HDAC6

亚型

IgG

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anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibody
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anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibody
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anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibody
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anti-Histone Deacetylase 6 (HDAC6) antibody
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anti-Histone Deacetylase 6 (HDAC6) antibody
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anti-Histone Deacetylase 6 (HDAC6) (N-Term) antibody
HDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) (pSer22) antibody
HDAC6 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

HDAC6 (Histone Deacetylase 6 (HDAC6))

别名

HDAC6 (HDAC6 产品)

别名

HD6 antibody, Hd6 antibody, Hdac5 antibody, Sfc6 antibody, mHDA2 antibody, CG6170 antibody, DHDAC2 antibody, DmHDAC2 antibody, Dmel\\CG6170 antibody, HDAC antibody, HDAC2 antibody, dHDAC2 antibody, dHDAC6 antibody, dmHDA404 antibody, hdac6 antibody, MGC53140 antibody, wu:fc31d02 antibody, dsim_GLEANR_17355 antibody, DsimGD17207 antibody, GD17207 antibody, HDAC6 antibody, ATHDA6 antibody, AXE1 antibody, HISTONE DEACETYLASE 6 antibody, MDC12.7 antibody, MDC12_7 antibody, RNA-MEDIATED TRANSCRIPTIONAL SILENCING 1 antibody, RPD3B antibody, RTS1 antibody, SIL1 antibody, histone deacetylase 6 antibody, histone deacetylase 6 antibody, Histone deacetylase 6 antibody, histone deacetylase 6 L homeolog antibody, GD17207 gene product from transcript GD17207-RB antibody, Histone DeAcetylase antibody, HDAC6 antibody, Hdac6 antibody, hdac6.L antibody, hdac6 antibody, Dsim\HDAC6 antibody, PTRG_03035 antibody, HDA6 antibody, hda-6 antibody

背景

Synonyms: HD6, JM21, CPBHM, PPP1R90, Histone deacetylase 6, HDAC6, KIAA0901
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer. In addition to its protein deacetylase activity, plays a key role in the degradation of misfolded proteins: when misfolded proteins are too abundant to be degraded by the chaperone refolding system and the ubiquitin-proteasome, mediates the transport of misfolded proteins to a cytoplasmic juxtanuclear structure called aggresome. Probably acts as an adapter that recognizes polyubiquitinated misfolded proteins and target them to the aggresome, facilitating their clearance by autophagy.

基因ID

10013

UniProt

Q9UBN7

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling