HDAC5 抗体 (Cy7)
Quick Overview for HDAC5 抗体 (Cy7) (ABIN681049)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
 - Cow, 人, 小鼠, 大鼠
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human HDAC5
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亚型
 - IgG
 
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应用备注
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                        IF(IHC-P)(1:100-500)
Optimal working dilution should be determined by the investigator. - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
 - HDAC5
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背景
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Synonyms: HDAC4: Histone deacetylase 4, HD4 HDAC 5, Histone deacetylase 5, HD5, Antigen NY-CO-9
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]..
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分子量
 - 122kDa
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基因ID
 - 9759, 10014
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UniProt
 - P56524, Q9UQL6
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途径
 - Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
 
抗原
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