TNFSF4 抗体
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- 抗原 See all TNFSF4 抗体
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFSF4 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Recognizes rat CD252, otherwise known as OX40L or CD134L, a 22kD type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium. The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease. Clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation.
- 纯化方法
- Protein G purified
- 免疫原
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ACI-S1 rat T-cell lymphoma cell line.
Type of Immunogen: Cells - 克隆位点
- ATM-2
- 亚型
- IgG1
- Top Product
- Discover our top product TNFSF4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Target Species of Antibody: Rat
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))
- 别名
- TNFSF4 / OX40L (TNFSF4 产品)
- 背景
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Name/Gene ID: TNFSF4
Family: TNF
Synonyms: TNFSF4, CD134 ligand, CD134L, CD252 antigen, Glycoprotein Gp34, OX-40L, OX40 ligand, TXGP1, OX40L, OX4OL, CD252, gp34, OX40 antigen ligand - 基因ID
- 7292
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints
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