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NQO1 抗体 (AA 201-274)

This anti-NQO1 antibody is a 兔 多克隆 antibody detecting NQO1 in WB, ELISA, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 7+ publications.
产品编号 ABIN678428
发货至: 中国

Quick Overview for NQO1 抗体 (AA 201-274) (ABIN678428)

抗原

See all NQO1 抗体
NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

适用

  • 72
  • 34
  • 33
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 9
  • 2
  • 2

克隆类型

  • 59
  • 21
多克隆

标记

  • 48
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NQO1 antibody is un-conjugated

应用范围

  • 62
  • 26
  • 22
  • 17
  • 17
  • 16
  • 13
  • 13
  • 9
  • 6
  • 3
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-274

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Pig,Horse,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human NQO1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Zhang, Qu, Zheng, Zhang, Zhou, Cui, Mo, Li, Xu, Gao: "Nrf2 antioxidant pathway suppresses Numb-mediated epithelial-mesenchymal transition during pulmonary fibrosis." in: Cell death & disease, Vol. 9, Issue 2, pp. 83, (2019) (PubMed).

    Zhang, Wang, Xie, Chen, Sinkemani, Yu, Wang, Mao, Wu: "Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence." in: Oncotarget, Vol. 9, Issue 2, pp. 2175-2192, (2018) (PubMed).

    Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." in: International immunopharmacology, Vol. 46, pp. 16-22, (2017) (PubMed).

    Tang, Gao, Mao, He, Liu, Cai, Lin, Wu: "Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-κB and TGF-β1/Smad-2/-3 pathways." in: Cell stress & chaperones, Vol. 21, Issue 2, pp. 239-49, (2016) (PubMed).

    Wang, Peng, Wei, Wei, Wang, Ma, Yao, Fu, Zu: "Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway." in: Biochimica et biophysica acta, Vol. 1850, Issue 9, pp. 1751-61, (2015) (PubMed).

    Zhao, Shi, Li, Li, Zhao: "Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro." in: Clinical and experimental pharmacology & physiology, (2015) (PubMed).

  • 抗原

    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

    别名

    NQO1

    背景

    Synonyms: DTD, QR1, DHQU, DIA4, NMOR1, NMORI, NAD(P)H dehydrogenase [quinone] 1, Azoreductase, DT-diaphorase, Menadione reductase, NAD(P)H:quinone oxidoreductase 1, Phylloquinone reductase, Quinone reductase 1, NQO1

    Background: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.

    基因ID

    1728

    UniProt

    P15559
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