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Hemagglutinin 抗体

The 兔 多克隆 anti-Hemagglutinin antibody is suitable to detect Hemagglutinin in samples from Influenza A Virus H1N1. It has been validated for ELISA, WB, IF (p), IF (cc), IHC (p) 和 IHC (fro).
产品编号 ABIN676553
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Hemagglutinin 抗体 (ABIN676553)

抗原

See all Hemagglutinin (HA) 抗体
Hemagglutinin (HA)

适用

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Influenza A Virus H1N1

宿主

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克隆类型

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多克隆

标记

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This Hemagglutinin antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Virus Strain

    A/California/04/2009

    交叉反应

    Virus

    交叉反应 (详细)

    Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)

    产品特性

    Antibody is specific for: Influenza A virus H1N1 (strain swl A/California/04/2009 H1N1)

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from Influenza A Virus Hemagglutinin (strain swl A/California/04/2009 H1N1)

    亚型

    IgG
  • 应用备注

    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Hemagglutinin (HA)

    物质类

    Influenza Protein

    背景

    Synonyms: HA, HA2, Hemagglutinin, Influenza A Virus (strain swl A/California/04/2009 H1N1)

    Background: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. Influenza A Virus (strain swl A/California/04/2009 H1N1)

    UniProt

    C3W5S1
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