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MCM3 抗体 (AA 251-350) (Biotin)

This anti-MCM3 antibody is a 兔 多克隆 antibody detecting MCM3 in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN676255
发货至: 中国

Quick Overview for MCM3 抗体 (AA 251-350) (Biotin) (ABIN676255)

抗原

See all MCM3 抗体
MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCM3 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 251-350

    预测反应

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MCM3

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

    别名

    MCM3

    背景

    Synonyms: minichromosome maintenance deficient 3, Cervical cancer proto oncogene 5, DNA polymerase alpha holoenzyme associated P1, DNA polymerase alpha holoenzyme associated protein P1, DNA replication factor MCM3, DNA replication licensing factor MCM3, HCC 5, HCC5, hRlf beta subunit, Human cervical cancer proto oncogene 5, MCM 3, MCM3 minichromosome maintenance deficient 3, MGC1157, Minichromosome maintenance deficient 3, Minichromosome maintenance protein 3, P1 h, P1 MCM3, P1 Protein, P1.h, P102 protein, Replication licensing factor beta subunit, RLF beta subunit, RLF subunit beta, RLFB.

    Background: MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

    基因ID

    4172

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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