CYLD 抗体 (N-Term)
Quick Overview for CYLD 抗体 (N-Term) (ABIN6756791)
抗原
See all CYLD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Human CYLD
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纯化方法
- Protein A purified
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免疫原
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A recombinant protein fragment from the N-terminal region of human CYLD.
Type of Immunogen: Recombinant protein -
亚型
- IgG
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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 170-338) antibody
CYLD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibodyCYLD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibodyCYLD 适用: 人, 小鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibodyCYLD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F7F4 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibodyCYLD 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibodyCYLD 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibodyCYLD 适用: 人, 小鼠, Hamster, 小鸡, Cow, 犬, 豚鼠, 马, 猴, 兔 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 305-582) antibodyCYLD 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1667CT857-3-6-1 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibodyCYLD 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Internal Region) antibodyVerified CYLD 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Approved: WB (2 - 5 μg/mL)
Usage: CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze-thaw cycles.
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- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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别名
- CYLD
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背景
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Name/Gene ID: CYLD
Synonyms: CYLD, CDMT, Deubiquitinating enzyme CYLD, CYLDI, EAC, HSPC057, MFT1, MFT, SBS, TEM, BRSS, Ubiquitin thiolesterase CYLD, USPL2, CYLD1, KIAA0849, Ubiquitin thioesterase CYLD -
基因ID
- 1540
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途径
- Apoptosis, Activation of Innate immune Response
抗原
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