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GZMB 抗体 (AA 21-130)

This anti-GZMB antibody is a 兔 多克隆 antibody detecting GZMB in WB, ELISA, FACS, IHC (p), IF (p), IHC (fro) 和 IF (cc). Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN675354
发货至: 中国

Quick Overview for GZMB 抗体 (AA 21-130) (ABIN675354)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

  • 178
  • 50
  • 26
  • 12
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠

宿主

  • 95
  • 91
  • 2

克隆类型

  • 102
  • 86
多克隆

标记

  • 101
  • 17
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GZMB antibody is un-conjugated

应用范围

  • 91
  • 83
  • 43
  • 41
  • 30
  • 24
  • 20
  • 17
  • 13
  • 13
  • 12
  • 9
  • 6
  • 6
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 53
    • 21
    • 15
    • 10
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-130

    特异性

    Specific towards Granzyme B and Granzyme H

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GZMB

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    Granzyme B

    背景

    Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    基因ID

    3002

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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