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PARK7/DJ1 抗体 (AA 101-189)

Name: PARK7/DJ1 抗体 (AA 101-189)
SKU: ABIN674739
Availability: OutOfStock

This anti-PARK7/DJ1 antibody is a 兔多克隆 antibody detecting PARK7/DJ1 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠.

Rat brain lysates probed with Anti PARK7 Polyclonal Antibody, Unconjugated at 1:200 overnight at 4˚C. (PARK7/DJ1 抗体 (AA 101-189))

Formalin-fixed and paraffin embedded mouse heart labeled with Anti-CAP1/PARK7 Polyclonal Antibody, Unconjugated (ABIN674739) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (PARK7/DJ1 抗体 (AA 101-189))

IHC

Formalin-fixed and paraffin embedded rat kidney labeled with Anti-CAP1/PARK7 Polyclonal Antibody, Unconjugated (ABIN674739) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (PARK7/DJ1 抗体 (AA 101-189))

IHC

Rat brain lysates probed with Anti CAP1/PARK7 Polyclonal Antibody, Unconjugated (ABIN674739) at 1:200 overnight at 4 °C. (PARK7/DJ1 抗体 (AA 101-189))

SDS

293T cells probed with PARK7 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (PARK7/DJ1 抗体 (AA 101-189))

FACS

5 images

产品编号 ABIN674739

发货至: 中国

Datasheet as PDF

Quick Overview for PARK7/DJ1 抗体 (AA 101-189) (ABIN674739)

抗原

See all PARK7/DJ1 (PARK7) 抗体

PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PARK7/DJ1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product PARK7 Primary Antibody

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AA 101-189

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig,Horse

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human PARK7

亚型

IgG
anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibody
PARK7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (C-Term) antibody
Verified PARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 山羊 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (C-Term) antibody
PARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibody
PARK7 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 1-188) antibody
PARK7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibody
PARK7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 2-189) antibody
PARK7 适用: 人, 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 1-189) antibody
PARK7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 130-164), (C-Term) antibody
PARK7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB49681 unconjugated

anti-Parkinson Protein 7 (PARK7) (AA 1-100) antibody
PARK7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))

别名

PARK7

背景

Synonyms: DJ1, DJ-1, HEL-S-67p, Protein deglycase DJ-1, Oncogene DJ1, Parkinson disease protein 7, PARK7
Background: Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) (PubMed:25416785). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease, functions probably related to its primary function (PubMed:17015834, PubMed:20304780, PubMed:18711745, PubMed:12796482, PubMed:19229105, PubMed:25416785). It is involved in neuroprotective mechanisms like the stabilization of NFE2L2 and PINK1 proteins, male fertility as a positive regulator of androgen signaling pathway as well as cell growth and transformation through, for instance, the modulation of NF-kappa-B signaling pathway (PubMed:12612053, PubMed:15502874, PubMed:14749723, PubMed:17015834, PubMed:21097510, PubMed:18711745). Its involvement in protein repair could also explain other unrelated functions. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death (PubMed:16390825). Required for correct mitochondrial morphology and function as well as for autophagy of dysfunctional mitochondria (PubMed:19229105, PubMed:16632486). Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking (PubMed:18711745). Regulates astrocyte inflammatory responses, may modulate lipid rafts-dependent endocytosis in astrocytes and neuronal cells (PubMed:23847046).

基因ID

11315

UniProt

Q99497

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport