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Estrogen Receptor alpha 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects Estrogen Receptor alpha in WB. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN6746024
发货至: 中国
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Quick Overview for Estrogen Receptor alpha 抗体 (C-Term) (ABIN6746024)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体
Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Estrogen Receptor alpha antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    Human ESR1 / Estrogen receptor

    预测反应

    Percent identity by BLAST analysis: Human (100%).

    纯化方法

    Immunoaffinity purified

    免疫原

    Synthetic peptide from C-Terminus of human ESR1 (P03372, NP_000116). Percent identity by BLAST analysis: Human (100%), Chimpanzee, Gorilla (92%), Baboon, Monkey (85%), Gibbon (84%).

    Type of Immunogen: Synthetic peptide
  • 应用备注

    Approved: WB (0.2 - 1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Distilled water

    浓度

    Lot specific

    缓冲液

    Lyophilized from PBS with 2 % sucrose

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    4 °C,-20 °C

    储存方法

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • He, Ting: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).

    Morgan, Thorburn, Pandolfi, Thorburn: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, (2002) (PubMed).

    Yount, Afshar, Ries, Korn, Shalev, Basila, McCormick, Haas-Kogan: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, (2001) (PubMed).

  • 抗原

    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

    别名

    ER Alpha / Estrogen Receptor

    背景

    Name/Gene ID: ESR1
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR1, Era, ERalpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

    基因ID

    2099

    NCBI登录号

    NP_000116

    UniProt

    P03372

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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