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GLI1 抗体 (AA 601-700)

This anti-GLI1 antibody is a 兔 多克隆 antibody detecting GLI1 in WB, ELISA, FACS, IF (cc), IHC (p), IF (p), ICC 和 IHC (fro). Suitable for 人, 小鼠, 大鼠 和 Pig. This Primary Antibody has been cited in 8+ publications.
产品编号 ABIN673374
发货至: 中国

Quick Overview for GLI1 抗体 (AA 601-700) (ABIN673374)

抗原

See all GLI1 抗体
GLI1 (Zinc Finger Protein GLI1 (GLI1))

适用

  • 72
  • 39
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  • 2
人, 小鼠, 大鼠, Pig

宿主

  • 61
  • 14
  • 3
  • 1

克隆类型

  • 56
  • 23
多克隆

标记

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  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This GLI1 antibody is un-conjugated

应用范围

  • 59
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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 601-700

    交叉反应

    人, 小鼠, Pig, 大鼠

    预测反应

    Dog,Cow,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GLI1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • Fan, Li, Liu, Cong, Zhao, Cao, Zheng: "Doxorubicin combined with low intensity ultrasound suppresses the growth of oral squamous cell carcinoma in culture and in xenografts." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 163, (2018) (PubMed).

    Yang, Wu, Feng, Huang, Liu, Liu, Chen: "Vitamin C plus hydrogel facilitates bone marrow stromal cell-mediated endometrium regeneration in rats." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 267, (2017) (PubMed).

    Long, Wang, Zheng, Lai, Xu, Hu, Lin, Zhang, Dong, Long, Tong, Liu: "Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 4, pp. 1288-302, (2016) (PubMed).

    Ma, Liu, Zeng, Zhou, Guo, Xie, Yang, Zheng, Xu, Wang, Chang, He, Li: "Silibinin induces apoptosis through inhibition of the mTOR-GLI1-BCL2 pathway in renal cell carcinoma." in: Oncology reports, Vol. 34, Issue 5, pp. 2461-8, (2015) (PubMed).

    Fan, Wang, Zhao, Liu, Chen, Sun, Zheng: "Sonic hedgehog signaling may promote invasion and metastasis of oral squamous cell carcinoma by activating MMP-9 and E-cadherin expression." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 7, pp. 41, (2014) (PubMed).

    Zhang, Zhu, Zhou, Gao, Yuan, Han: "Serotonin receptor 2C and insulin secretion." in: PLoS ONE, Vol. 8, Issue 1, pp. e54250, (2013) (PubMed).

    Yue, Zhong, Pei, Xiao, Zhang, Jiang, Zhang, Chen, Yang, Dang, Chang: "Aberrant activation of hedgehog pathway in nasopharyngeal carcinoma." in: Clinical and experimental medicine, Vol. 13, Issue 4, pp. 315-22, (2013) (PubMed).

    Du, Feng, Wang, Piao, Cui, Chen, Lei, Sun, Liu, Wang, Li, Yang, Sun, Zhao, Jiang, Li, Jiang: "Curcumin suppresses malignant glioma cells growth and induces apoptosis by inhibition of SHH/GLI1 signaling pathway in vitro and vivo." in: CNS neuroscience & therapeutics, Vol. 19, Issue 12, pp. 926-36, (2013) (PubMed).

  • 抗原

    GLI1 (Zinc Finger Protein GLI1 (GLI1))

    别名

    GLI1

    背景

    Synonyms: GLI, Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, GLI1

    Background: Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.

    基因ID

    2735

    UniProt

    P08151

    途径

    Hedgehog Signaling, Dopaminergic Neurogenesis
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