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Interleukin 17a 抗体 (PE)

This anti-Interleukin 17a antibody is a 大鼠 单克隆 antibody detecting Interleukin 17a in ICFC. Suitable for 小鼠.
产品编号 ABIN6728583
发货至: 中国

Quick Overview for Interleukin 17a 抗体 (PE) (ABIN6728583)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

  • 85
  • 46
  • 19
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
小鼠

宿主

  • 66
  • 38
  • 16
  • 5
  • 2
  • 2
大鼠

克隆类型

  • 71
  • 57
  • 1
单克隆

标记

  • 68
  • 21
  • 14
  • 8
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Interleukin 17a antibody is conjugated to PE

应用范围

  • 75
  • 56
  • 27
  • 24
  • 14
  • 11
  • 10
  • 9
  • 8
  • 8
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Intracellular Flow Cytometry (ICFC)

克隆位点

TC11-18H10-1
  • 亚型

    IgG1, kappa
  • 应用备注

    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

    说明

    Matching Isotype Control: PE Rat IgG1, κ Isotype Control (ABIN7469822)

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300, 1 % BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL-17A

    背景

    Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8,IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.

    基因ID

    16171

    UniProt

    Q62386
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