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PD-L1 抗体 (APC)

PD-L1 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 10F-9G2 APC
产品编号 ABIN6727419
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    适用
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    小鼠
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    大鼠
    克隆类型
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    单克隆
    标记
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    This PD-L1 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    克隆位点
    10F-9G2
    亚型
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
    说明

    Matching Isotype Control: APC Rat IgG2b, κ Isotype Control (ABIN7469860)

    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.05 % Proclin300, 1 % BSA
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274/PD-L1 (PD-L1 产品)
    背景
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
    基因ID
    60533
    UniProt
    Q9EP73
    途径
    Cancer Immune Checkpoints
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