PD-L1 抗体 (APC)
Quick Overview for PD-L1 抗体 (APC) (ABIN6727419)
抗原
See all PD-L1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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亚型
- IgG2b, kappa
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应用备注
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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说明
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Matching Isotype Control: APC Rat IgG2b, κ Isotype Control (ABIN7469860)
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- PD-L1 (CD274 (PD-L1))
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别名
- CD274/PD-L1
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背景
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
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基因ID
- 60533
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UniProt
- Q9EP73
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途径
- Cancer Immune Checkpoints
抗原
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