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BIRC7 抗体 (AA 101-200)

Name: BIRC7 抗体 (AA 101-200)
SKU: ABIN672561
Availability: OutOfStock

This anti-BIRC7 antibody is a 兔多克隆 antibody detecting BIRC7 in WB, ELISA, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 2+ publications.

Mouse Lymph node lysates probed with Livin Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (BIRC7 抗体 (AA 101-200))

Formalin-fixed and paraffin embedded Human endometrium carcinoma labeled Anti-Livin Polyclonal Antibody, Unconjugated (ABIN672561) at 1:200, followed by conjugation to the secondary antibody and DAB staining (BIRC7 抗体 (AA 101-200))

IHC

Formalin-fixed and paraffin embedded Human endometrium carcinoma labeled Anti-Livin Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (BIRC7 抗体 (AA 101-200))

IHC (p)

3 images

(2 references)

产品编号 ABIN672561

发货至: 中国

Quick Overview for BIRC7 抗体 (AA 101-200) (ABIN672561)

抗原

See all BIRC7 抗体

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This BIRC7 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

抗原表位
14

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1

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1
AA 101-200

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Livin

亚型

IgG
anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) antibody
BIRC7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibody
Verified BIRC7 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 264-280) antibody
BIRC7 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-90) antibody
BIRC7 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3H1 unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 87-298) antibody
BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibody
BIRC7 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-265) antibody
BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (C-Term) antibody
BIRC7 适用: 人, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (AA 1-298) antibody
BIRC7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Baculoviral IAP Repeat-Containing 7 (BIRC7) (N-Term) antibody
BIRC7 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

Zhang, Peng, Luo, Zhou: "Prospective experimental studies on the renal protective effect of ulinastatin after paraquat poisoning." in: World journal of emergency medicine, Vol. 3, Issue 4, pp. 299-304, (2014) (PubMed).
抗原

BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

别名

Livin

背景

Synonyms: KIAP, LIVIN, MLIAP, RNF50, ML-IAP, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, Melanoma inhibitor of apoptosis protein, RING finger protein 50, BIRC7, UNQ5800/PRO19607/PRO21344
Background: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.

基因ID

79444

UniProt

Q96CA5