TCP1 alpha/CCTA 抗体 (AA 361-450)
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- 抗原 See all TCP1 alpha/CCTA (TCP1) 抗体
- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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抗原表位
- AA 361-450
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TCP1 alpha/CCTA antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human p63 protein
- 亚型
- IgG
- Top Product
- Discover our top product TCP1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair." in: PLoS pathogens, Vol. 12, Issue 6, pp. e1005544, (2016) (PubMed).
: "An improved method for the isolation and culture of rat epidermal stem cells." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2529-34, (2014) (PubMed).
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Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair." in: PLoS pathogens, Vol. 12, Issue 6, pp. e1005544, (2016) (PubMed).
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- 抗原
- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
- 别名
- p63 (TCP1 产品)
- 背景
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Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
Subcellular location: Nucleus
Synonyms: AIS, KET, LMS, NBP, RHS, p4, p51, p63, EEC3, OFC8, p73H, p73L, SHFM4, TP53L, TP73L, p53CP, TP53CP, B(p51A), B(p51B), Tumor protein 63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like
- 基因ID
- 8626
- UniProt
- Q9H3D4
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