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TCP1 alpha/CCTA 抗体 (AA 361-450)

TCP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN672336
发货至: 中国
  • 抗原 See all TCP1 alpha/CCTA (TCP1) 抗体
    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
    抗原表位
    • 39
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    AA 361-450
    适用
    • 173
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    人, 小鼠, 大鼠
    宿主
    • 155
    • 26
    • 18
    • 1
    • 1
    克隆类型
    • 146
    • 55
    多克隆
    标记
    • 68
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    This TCP1 alpha/CCTA antibody is un-conjugated
    应用范围
    • 127
    • 52
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    • 45
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    • 39
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    • 22
    • 22
    • 12
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    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human p63 protein
    亚型
    IgG
    Top Product
    Discover our top product TCP1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Quantius, Schmoldt, Vazquez-Armendariz, Becker, El Agha, Wilhelm, Morty, Vadász, Mayer, Gattenloehner, Fink, Matrosovich, Li, Seeger, Lohmeyer, Bellusci, Herold: "Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair." in: PLoS pathogens, Vol. 12, Issue 6, pp. e1005544, (2016) (PubMed).

    Yang, Xie, Shu, Liu, Chen, Ruan, Qi: "An improved method for the isolation and culture of rat epidermal stem cells." in: International journal of clinical and experimental pathology, Vol. 6, Issue 11, pp. 2529-34, (2014) (PubMed).

  • 抗原
    TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
    别名
    p63 (TCP1 产品)
    背景

    Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.

    Subcellular location: Nucleus

    Synonyms: AIS, KET, LMS, NBP, RHS, p4, p51, p63, EEC3, OFC8, p73H, p73L, SHFM4, TP53L, TP73L, p53CP, TP53CP, B(p51A), B(p51B), Tumor protein 63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like

    基因ID
    8626
    UniProt
    Q9H3D4
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