CRB1 抗体
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- 抗原 See all CRB1 抗体
- CRB1 (Crumbs Homolog 1 (CRB1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CRB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit IgG polyclonal antibody for CRB1 detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 序列
- FRTRDANVII LHAEKEPEFL NISIQDSRLF FQLQ
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for CRB1 detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence of human CRB1 (FRTRDANVIILHAEKEPEFLNISIQDSRLFFQLQ).
- 亚型
- IgG
- Top Product
- Discover our top product CRB1 Primary Antibody
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- CRB1 (Crumbs Homolog 1 (CRB1))
- 别名
- CRB1 (CRB1 产品)
- 别名
- CRB1 antibody, si:dkey-114d20.6 antibody, si:dkey-114d20.7 antibody, LCA8 antibody, RP12 antibody, 7530426H14Rik antibody, A930008G09Rik antibody, crumbs 1, cell polarity complex component antibody, crumbs family member 1, photoreceptor morphogenesis associated antibody, CRB1 antibody, crb1 antibody, Crb1 antibody
- 背景
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Synonyms: Protein crumbs homolog 1, CRB1
Background: Crumbs homolog 1 is a protein that in humans is encoded by the CRB1 gene. This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.
- 基因ID
- 23418
- UniProt
- P82279
- 途径
- Notch Signaling
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