PTCRA 抗体 (AA 24-143)
Quick Overview for PTCRA 抗体 (AA 24-143) (ABIN6719646)
抗原
See all PTCRA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-143
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原理
- Anti-PTCRA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PTCRA Antibody Picoband® (ABIN6719646). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human PTCRA recombinant protein (Position: T24-T143).
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亚型
- IgG
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anti-Pre T-Cell Antigen Receptor alpha (PTCRA) (AA 172-281) antibody
PTCRA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pre T-Cell Antigen Receptor alpha (PTCRA) (AA 197-225), (C-Term) antibodyPTCRA 适用: 人 WB 宿主: 兔 Polyclonal RB39212 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Aifantis, I., Borowski, C., Gounari, F., Lacorazza, H. D., Nikolich-Zugich, J., von Boehmer, H. A critical role for the cytoplasmic tail of pT-alpha in T lymphocyte development. Nature Immun. 3: 483-488, 2002. Note: Erratum: Nature Immun. 3: 591 only, 2002. 2. Del Porto, P., Bruno, L., Mattei, M.-G., von Boehmer, H., Saint-Ruf, C. Cloning and comparative analysis of the human pre-T-cell receptor alpha-chain gene. Proc. Nat. Acad. Sci. 92: 12105-12109, 1995. 3. Saint-Ruf, C., Lechner, O., Feinberg, J., von Boehmer, H. Genomic structure of the human pre-T cell receptor alpha chain and expression of two mRNA isoforms. Europ. J. Immun. 28: 3824-3831, 1998. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PTCRA (Pre T-Cell Antigen Receptor alpha (PTCRA))
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别名
- PTCRA
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背景
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Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
Background: This PTCRA gene is mapped to 6p21.1. The protein encoded by this gene is a single-pass type I membrane protein that is found in immmature but not mature T-cells. Along with TCRB and CD3 complex, the encoded protein forms the pre-T-cell receptor complex, which regulates early T-cell development. Four transcript variants encoding different isoforms have been found for this gene.
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分子量
- 29 kDa
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基因ID
- 171558
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途径
- Cancer Immune Checkpoints
抗原
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