PDCD10 抗体 (AA 1-212) (DyLight 550)
Quick Overview for PDCD10 抗体 (AA 1-212) (DyLight 550) (ABIN7354691)
抗原
See all PDCD10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-212
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原理
- Anti-Human PDCD10 DyLight® 550 conjugated Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human PDCD10 DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human PDCD10 recombinant protein (Position: M1-A212).
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亚型
- IgG
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: PDCD10 programmed cell death 10". 2. Bergametti F, Denier C, Labauge P, Arnoult M, Boetto S, Clanet M, Coubes P, Echenne B, Ibrahim R, Irthum B, Jacquet G, Lonjon M, Moreau JJ, Neau JP, Parker F, Tremoulet M, Tournier-Lasserve E (Jan 2005). "Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations". American Journal of Human Genetics. 76 (1): 42-51.
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- PDCD10 (Programmed Cell Death 10 (PDCD10))
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别名
- PDCD10
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背景
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Synonyms: Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15
Tissue Specificity: Ubiquitous.
Background: Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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分子量
- 39 kDa
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基因ID
- 11235
抗原
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