RRBP1 抗体
Quick Overview for RRBP1 抗体 (ABIN6719628)
抗原
See all RRBP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Anti-RRBP1 Antibody Picoband®
-
序列
- EKEKKLTSDL GRAATRLQEL LKTTQEQLAR EKDTVKKLQE QLEKAED
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-RRBP1 Antibody Picoband® (ABIN6719628). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RRBP1, which shares 87.2% and 89.4% amino acid (aa) sequence identity with mouse and rat RRBP1, respectively.
-
亚型
- IgG
-
-
anti-Ribosome Binding Protein 1 (RRBP1) (C-Term) antibody
KO Validated RRBP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ribosome Binding Protein 1 (RRBP1) (AA 1-140) antibodyRRBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ribosome Binding Protein 1 (RRBP1) antibodyRRBP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ribosome Binding Protein 1 (RRBP1) (AA 180-229) antibodyRRBP1 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Basson, C. T., MacRae, C. A., Schoenberg-Fejzo, M., Morton, C. C., Spinner, N. B., Genin, A., Krug, E., Seidman, J. G., Seidman, C. E. Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Genomics 35: 628-631, 1996. 2. Rezaee, M., Isokawa, K., Halligan, N., Markwald, R. R., Krug, E. L. Identification of an extracellular 130 kDa protein involved in early cardiac morphogenesis. J. Biol. Chem. 268: 14404-14411, 1993. 3. Basson CT, MacRae CA, Schoenberg-Fejzo M, Morton CC, Spinner NB, Genin A, Krug E, Seidman JG, Seidman CE (Dec 1996). "Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130". Genomics. 35 (3): 628-31. -
说明
-
Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- RRBP1 (Ribosome Binding Protein 1 (RRBP1))
-
别名
- RRBP1
-
背景
-
Synonyms: Ribosome-binding protein 1, 180 kDa ribosome receptor homolog, RRp, ES/130-related protein, Ribosome receptor protein, RRBP1, KIAA1398
Tissue Specificity: Expressed in kidney.
Background: Ribosome-binding protein 1, also referred to as p180, is a protein that in humans is encoded by the RRBP1 gene. It is mapped to 20p12.1. This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
-
分子量
- 200 kDa
-
基因ID
- 6238
-
UniProt
- Q9P2E9
抗原
-
