PDE4D 抗体 (AA 466-709) (DyLight 550)
Quick Overview for PDE4D 抗体 (AA 466-709) (DyLight 550) (ABIN7354588)
抗原
See all PDE4D 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 466-709
-
原理
- Anti-Human PDE4D DyLight® 550 conjugated Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Human PDE4D DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human PDE4D recombinant protein (Position: H466-Q709).
-
亚型
- IgG
-
-
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibody
Verified PDE4D 适用: 人 WB, ELISA, IHC, EIA 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 164-213) antibodyPDE4D 适用: 人, 小鼠, 大鼠, 马, 小鸡, Pig, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 466-709) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D 适用: 人, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (C-Term) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 401-550) antibodyPDE4D 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) (AA 581-809) antibodyPDE4D 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 4D, cAMP-Specific (PDE4D) antibodyPDE4D 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. "Entrez Gene: PDE4D phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)". 2. Michot C, Le Goff C, Goldenberg A, Abhyankar A, Klein C, Kinning E, Guerrot AM, Flahaut P, Duncombe A, Baujat G, Lyonnet S, Thalassinos C, Nitschke P, Casanova JL, Le Merrer M, Munnich A, Cormier-Daire V (Apr 2012). "Exome sequencing identifies PDE4D mutations as another cause of acrodysostosis". American Journal of Human Genetics. 90 (4): 740-5.
-
说明
-
Other applications have not been tested. Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
-
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
-
别名
- PDE4D
-
背景
-
Synonyms: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, DPDE3, PDE43, PDE4D, DPDE3
Tissue Specificity: Expressed in colonic epithelial cells (at protein level). Widespread, most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Background: cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene. This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
-
分子量
- 39 kDa
-
基因ID
- 5144
-
UniProt
- Q08499
-
途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
-
