MTUS1 抗体 (AA 1038-1236)
Quick Overview for MTUS1 抗体 (AA 1038-1236) (ABIN6719607)
抗原
See all MTUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1038-1236
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原理
- Anti-MTUS1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MTUS1 Antibody Picoband® (ABIN6719607). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MTUS1 recombinant protein (Position: D1038-N1236).
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亚型
- IgG
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anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1018-1270) antibody
MTUS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1-240) antibodyMTUS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (Middle Region) antibodyMTUS1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1151-1270) antibodyMTUS1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1-196) antibodyMTUS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1041-1270) antibodyMTUS1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) antibodyMTUS1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 1020-1210) antibodyMTUS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (N-Term) antibodyMTUS1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 兔, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Microtubule Associated Tumor Suppressor 1 (MTUS1) (AA 983-1017) antibodyMTUS1 适用: 人 WB 宿主: 兔 Polyclonal RB54732 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Nouet, S., Amzallag, N., Li, J.-M., Louis, S., Seitz, I., Cui, T.-X., Alleaume, A.-M., Di Benedetto, M., Boden, C., Masson, M., Strosberg, A. D., Horiuchi, M., Couraud, P.-O., Nahmias, C. Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP. J. Biol. Chem. 279: 28989-28997, 2004. 2. Ohi, R., Coughlin, M. L., Lane, W. S., Mitchison, T. J. An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin. Dev. Cell 5: 309-321, 2003. 2. Seibold, S., Rudroff, C., Weber, M., Galle, J., Wanner, C., Marx, M. Identification of a new tumor suppressor gene located at chromosome 8p21.3-22. FASEB J. 17: 1180-1182, 2003. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))
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别名
- MTUS1
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背景
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Synonyms: Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1
Tissue Specificity: Ubiquitously expressed (at protein level). Highly expressed in brain. Down-regulated in ovarian carcinoma, pancreas carcinoma, colon carcinoma and head and neck squamous cell carcinoma (HNSCC). Isoform 1 is the major isoform in most peripheral tissues. Isoform 2 is abundant in most peripheral tissues. Isoform 3 is the major isoform in brain, female reproductive tissues, thyroid and heart. Within brain it is highly expressed in corpus callosum and pons. Isoform 6 is brain-specific, it is the major isoform in cerebellum and fetal brain.
Background: Mitochondrial tumor suppressor 1 (MTSG1) or Microtubule-Associated Scaffold Protein 1 (MTUS1) is a candidate tumor suppressor protein encoded by the MTUS1 gene in humans. It is mapped to 8p22. This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
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分子量
- 170 kDa
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基因ID
- 57509
抗原
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