MTUS1 抗体 (Middle Region)
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北京 101111
Quick Overview for MTUS1 抗体 (Middle Region) (ABIN2781855)
抗原
See all MTUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- MTUS1 Antibody - middle region
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序列
- KRLSMENEEL LWKLHNGDLC SPKRSPTSSA IPLQSPRNSG SFPSPSISPR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against MTUS1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MTUS1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44419-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))
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别名
- MTUS1
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背景
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Background Information: MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
Gene Name: Microtubule associated tumor suppressor 1
Alternative Symbols: ATBP, ATIP, ICIS, MP44, ATIP3, MTSG1
Protein Name: Microtubule-associated tumor suppressor 1
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分子量
- 141kDa
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基因ID
- 57509
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NCBI登录号
- NP_001001924
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UniProt
- Q9ULD2
抗原
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