CCL2 抗体 (AA 24-96)
Quick Overview for CCL2 抗体 (AA 24-96) (ABIN6719598)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-96
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原理
- Anti-CCL2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-CCL2 Antibody Picoband® (ABIN6719598). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat CCL2 recombinant protein (Position: Q24-R96).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibody
CCL2 适用: 人, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 61-148) antibodyCCL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人 WB, IHC, ELISA, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96) antibodyCCL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89), (C-Term) antibodyCCL2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB17838 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人, 小鼠, 猴 WB, IHC (p), IF, FACS, EIA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 31-80) antibodyCCL2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Furutani, Y., Nomura, H., Notake, M., Oyamada, Y., Fukui, T., Yamada, M., Larsen, C. G., Oppenheim, J. J., Matsushima, K. Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem. Biophys. 2. Gosling, J., Slaymaker, S., Gu, L., Tseng, S., Zlot, C. H., Young, S. G., Rollins, B. J., Charo, I. F. MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J. Clin. Invest. 103: 773-778, 1999. 3. Gu, L., Okaka, Y., Clinton, S. K., Gerard, C., Sukhova, G. K., Libby, P., Rollins, B. J. Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low absorbance lipoprotein receptor-deficient mice. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- Ccl2
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背景
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Synonyms: C-C motif chemokine 2, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Monocyte chemotactic protein 1, MCP-1, Small-inducible cytokine A2, Ccl2, Je, Mcp1, Scya2
Tissue Specificity: Detected in various tissues including thymus, liver, lung, heart, and adult ovary.
Background: Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.
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分子量
- 11 kDa
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基因ID
- 24770
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UniProt
- P14844
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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