MUC13 抗体 (AA 226-312)
Quick Overview for MUC13 抗体 (AA 226-312) (ABIN6719597)
抗原
See all MUC13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 226-312
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原理
- Anti-MUC13 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MUC13 Antibody Picoband® (ABIN6719597). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MUC13 recombinant protein (Position: E226-S312).
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亚型
- IgG
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anti-Mucin 13, Cell Surface Associated (MUC13) (C-Term) antibody
MUC13 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (Extracellular Domain) antibodyMUC13 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (C-Term) antibodyMUC13 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (Internal Region) antibodyVerified MUC13 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (C-Term) antibodyMUC13 适用: 人 WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (AA 421-470) antibodyMUC13 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (C-Term) antibodyMUC13 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (AA 175-270) antibodyMUC13 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mucin 13, Cell Surface Associated (MUC13) (AA 174-404) antibodyMUC13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Shimamura, T., Ito, H., Shibahara, J., Watanabe, A., Hippo, Y., Taniguchi, H., Chen, Y., Kashima, T., Ohtomo, T., Tanioka, F., Iwanari, H., Kodama, T., Kazui, T., Sugimura, H., Fukayama, M., Aburatani, H. Overexpression of MUC13 is associated with intestinal-type gastric cancer. Cancer Sci. 96: 265-273, 2005. 2. Williams, S. J., Wreschner, D. H., Tran, M., Eyre, H. J., Sutherland, G. R., McGuckin, M. A. MUC13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells. J. Biol. Chem. 276: 18327-18336, 2001. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MUC13 (Mucin 13, Cell Surface Associated (MUC13))
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别名
- MUC13
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背景
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Synonyms: Mucin-13, MUC-13, Down-regulated in colon cancer 1, MUC13, DRCC1, RECC, UNQ6194, PRO20221
Tissue Specificity: Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.
Background: Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues. It is mapped to 3q21.2. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most animals. Mucins' key characteristic is their ability to form gels, therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. They often take an inhibitory role. Some mucins are associated with controlling mineralization, including nacre formation in mollusks,calcification in echinoderms and bone formation in vertebrates. They bind to pathogens as part of the immune system. Overexpression of the mucin proteins, especially MUC1, is associated with many types of cancer. Although some mucins are membrane-bound due to the presence of a hydrophobic membrane-spanning domain that favors retention in the plasma membrane, most mucins are secreted as principal components of mucus by mucous membranes or are secreted to become a component of saliva.
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分子量
- 55 kDa
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基因ID
- 56667
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UniProt
- Q9H3R2
抗原
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