CD81 抗体 (AA 113-201) (DyLight 550)
Quick Overview for CD81 抗体 (AA 113-201) (DyLight 550) (ABIN7354597)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 113-201
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原理
- Anti-Human TAPA1 DyLight® 550 conjugated CD81 Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Human TAPA1 DyLight® 550 conjugated CD81 Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human TAPA1 recombinant protein (Position: F113-K201).
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亚型
- IgG
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应用备注
- Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Andria ML, Hsieh CL, Oren R, Francke U, Levy S (August 1991)."Genomic organization and chromosomal localization of the TAPA-1 gene".Journal of Immunology. 147 (3): 1030-6. 2. Levy S, Todd SC, Maecker HT (1998). "CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system.".Annu Rev Immunol. 16: 89-109.
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说明
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Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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- CD81
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别名
- CD81
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背景
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Synonyms: CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28, CD81, CD81, TAPA1, TSPAN28
Tissue Specificity: Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.
Background: CD81 Molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 39 kDa
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基因ID
- 975
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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