MR1 抗体 (AA 23-269)
Quick Overview for MR1 抗体 (AA 23-269) (ABIN6719587)
抗原
See all MR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-269
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原理
- Anti-MR1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MR1 Antibody (ABIN6719587). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human MR1 recombinant protein (Position: R23-D269).
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亚型
- IgG
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anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibody
MR1 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 312-341), (C-Term) antibodyMR1 适用: 人 WB 宿主: 兔 Polyclonal RB37199 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 适用: 人, 小鼠 ELISA, WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibodyMR1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: MR1 major histocompatibility complex, class I-related". 2. Hashimoto K, Hirai M, Kurosawa Y (Aug 1995). "A gene outside the human MHC related to classical HLA class I genes". Science. 269 (5224): 693-5. 3. Yamaguchi H, Kurosawa Y, Hashimoto K (Nov 1998). "Expanded genomic organization of conserved mammalian MHC class I-related genes, human MR1 and its murine ortholog". Biochem Biophys Res Commun. 250 (3): 558-64. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
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别名
- MR1
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背景
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Synonyms: Major histocompatibility complex class I-related gene protein, MHC class I-related gene protein, Class I histocompatibility antigen-like protein, MR1
Tissue Specificity: Ubiquitous.
Background: Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
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分子量
- 40 kDa
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基因ID
- 3140
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UniProt
- Q95460
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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