PLA2G7 抗体 (AA 176-415)
Quick Overview for PLA2G7 抗体 (AA 176-415) (ABIN6719581)
抗原
See all PLA2G7 (Lp-PLA2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-415
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原理
- Anti-PAFAH/PLA2G7 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-PAFAH/PLA2G7 Antibody Picoband® (ABIN6719581). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human PAFAH recombinant protein (Position: A176-N415).
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亚型
- IgG
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anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 301-441) antibody
Lp-PLA2 适用: 人, 小鼠, 大鼠, Pig, 兔 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) antibodyLp-PLA2 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3E1G5 unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 200-228) antibodyLp-PLA2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21322 unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) antibodyLp-PLA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2A1B6 unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 49-441) antibodyLp-PLA2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) antibodyLp-PLA2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 5D1 unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-441) antibodyLp-PLA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-444) antibodyLp-PLA2 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 207-236), (Middle Region) antibodyLp-PLA2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipoprotein-Associated phospholipase A2 (Lp-PLA2) (AA 22-440) antibodyLp-PLA2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Claud, E. C., Li, D., Xiao, Y., Caplan, M. S., Jilling, T. Platelet-activating factor regulates chloride transport in colonic epithelial cell monolayers. Pediat. Res. 52: 155-162, 2002. 2. Jang, Y., Kim, O. Y., Koh, S. J., Chae, J. S., Ko, Y. G., Kim, J. Y., Cho, H., Jeong, T.-S., Lee, W. S., Ordovas, J. M., Lee, J. H. The val279phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J. Clin. Endocr. Metab. 91: 3521-3527, 2006. 3. Lp-PLA2 Studies Collaboration. Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies.Lancet 375: 1536-1544, 2010. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))
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别名
- PLA2G7
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背景
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Synonyms: Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA (2), PAF 2-acylhydrolase, PLA2G7, PAFAH
Tissue Specificity: Plasma.
Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme that in humans is encoded by the PLA2G7 gene. Lp-PLA2 is a 45- kDa protein of 441 amino acids. It is one of several PAF acetylhydrolases. In the blood it travels mainly with low-density lipoprotein (LDL). Less than 20 % is associated with high-density lipoprotein HDL. It is an enzyme produced by inflammatory cells and hydrolyzes oxidized phospholipids in LDL. Lp-PLA2 is platelet-activating factor (PAF) acetylhydrolase, a secreted enzyme that catalyzes the degradation of PAF to inactive products by hydrolysis of the acetyl group at the sn-2 position, producing the biologically inactive products LYSO-PAF and acetate.
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分子量
- 50 kDa
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基因ID
- 7941
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UniProt
- Q13093
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途径
- Peptide Hormone Metabolism
抗原
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