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CD2AP 抗体 (AA 253-337)

Cd2ap 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 5F8 unconjugated
产品编号 ABIN6719544
发货至: 中国
  • 抗原 See all CD2AP (Cd2ap) 抗体
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    抗原表位
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 253-337
    适用
    人, 大鼠, 小鼠
    宿主
    • 23
    • 1
    • 1
    小鼠
    克隆类型
    • 24
    • 1
    单克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD2AP antibody is un-conjugated
    应用范围
    • 13
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    原理
    Mouse IgG monoclonal antibody for CD2AP detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Mouse IgG monoclonal antibody for CD2AP detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human CD2AP recombinant protein (Position: K253-K337).
    克隆位点
    5F8
    亚型
    IgG
    Top Product
    Discover our top product Cd2ap Primary Antibody
  • 应用备注

    Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Flow Cytometry|1-3 μg/1x106 cells

    说明

    Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    缓冲液
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
    别名
    CD2AP (Cd2ap 产品)
    别名
    cd2apl antibody, fj51c01 antibody, im:7153970 antibody, si:ch211-207n9.1 antibody, wu:fj51c01 antibody, zgc:103705 antibody, DKFZp469E061 antibody, CMS antibody, AL024079 antibody, C78928 antibody, METS-1 antibody, Mets1 antibody, CD2-associated protein L homeolog antibody, CD2 associated protein antibody, CD2-associated protein antibody, cd2ap.L antibody, CD2AP antibody, cd2ap antibody, Cd2ap antibody
    背景

    Synonyms: CD2-associated protein, Adapter protein CMS, Cas ligand with multiple SH3 domains, CD2AP

    Background: CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

    基因ID
    23607
    UniProt
    Q9Y5K6
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