DOK7 抗体
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- 抗原 See all DOK7 抗体
- DOK7 (Docking Protein 7 (DOK7))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 原理
- Rabbit IgG polyclonal antibody for DOK7 detection. Tested with WB, IHC-P, ICC/IF in Human,Mouse,Rat.
- 序列
- STVEERVAQE ALETLQLEKR LSLLSHAGR
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for DOK7 detection. Tested with WB, IHC-P, ICC/IF in Human,Mouse,Rat.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence of human DOK7(STVEERVAQEALETLQLEKRLSLLSHAGR).
- 亚型
- IgG
- Top Product
- Discover our top product DOK7 Primary Antibody
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anti-Docking Protein 7 (DOK7) antibody
DOK7 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 7E2 unconjugated
anti-Docking Protein 7 (DOK7) (N-Term) antibodyDOK7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) (AA 416-504) antibodyDOK7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) (C-Term) antibodyDOK7 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) antibodyDOK7 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Docking Protein 7 (DOK7) antibodyDOK7 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5C6 unconjugated
anti-Docking Protein 7 (DOK7) (AA 63-320) antibodyDOK7 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) (AA 10-59) antibodyDOK7 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) (AA 21-120) antibodyDOK7 适用: 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 7 (DOK7) (AA 402-451) antibodyDOK7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Immunocytochemistry/Immunofluorescence|2 μg/mL
- 说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- DOK7 (Docking Protein 7 (DOK7))
- 别名
- DOK7 (DOK7 产品)
- 别名
- si:dkey-180b4.3 antibody, si:ch211-164d19.2 antibody, C4orf25 antibody, CMS1B antibody, A930013K19Rik antibody, AW049091 antibody, Dok-7 antibody, EF-12 antibody, Oit5 antibody, RGD1566416 antibody, dok-7 antibody, docking protein 7 antibody, DOK7 antibody, dok7 antibody, Dok7 antibody
- 背景
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Synonyms: Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25,
Background: Dok-7 is a non-catalytic cytoplasmic adaptor protein that is expressed specifically in muscle and is essential for the formation of neuromuscular synapses. Further, Dok-7 contains pleckstrin homology (PH) and phosphotyrosine-binding (PTB) domains that are critical for Dok-7 function. It is mapped to 4p16.3. The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
- 基因ID
- 285489
- 途径
- Skeletal Muscle Fiber Development
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