DOK7 抗体 (AA 10-59)
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北京 101111
Quick Overview for DOK7 抗体 (AA 10-59) (ABIN1533938)
抗原
See all DOK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-59
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原理
- Dok-7 Antibody
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特异性
- Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human DOK7. AA range:10-59
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DOK7 (Docking Protein 7 (DOK7))
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别名
- DOK7
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背景
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Synonyms: DOK7, C4orf25, Protein Dok-7, Downstream of tyrosine kinase 7
Background: docking protein 7(DOK7) Homo sapiens The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009],
Gene Name: DOK7
Protein Name: Protein Dok-7
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分子量
- 53 kDa
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基因ID
- 285489
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OMIM
- 254300
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UniProt
- Q18PE1
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途径
- Skeletal Muscle Fiber Development
抗原
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