LCP1 抗体
Quick Overview for LCP1 抗体 (ABIN6719421)
抗原
See all LCP1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-Plastin L/LCP1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Plastin L/LCP1 Antibody Picoband® (ABIN6719421). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Plastin L/LCP1 recombinant protein (M1-K444).
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亚型
- IgG
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anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 5-233) antibody
LCP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 2-627) antibodyLCP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 2-627) antibodyLCP1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (Headpiece Region) antibodyLCP1 适用: 人 WB, IHC, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 1-270) antibodyLCP1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) antibodyLCP1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) antibodyLCP1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 138-172), (N-Term) antibodyLCP1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB46580 unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 305-339) antibodyLCP1 适用: 斑马鱼 WB 宿主: 兔 Polyclonal RB46566 unconjugated
anti-Lymphocyte Cytosolic Protein 1 (LCP1) (AA 1-627) antibodyLCP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
ELISA, 0.1-0.5 μg/mL
1. Chen, H., Mocsai, A., Zhang, H., Ding, R.-X., Morisaki, J. H., White, M., Rothfork, J. M., Heiser, P., Colucci-Guyon, E., Lowell, C. A., Gresham, H. D., Allen, P. M., Brown, E. J. Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading. Immunity 19: 95-104, 2003. 2. Galiegue-Zouitina, S., Quief, S., Hildebrand, M.-P., Denis, C., Detourmignies, L., Lai, J.-L., Kerckaert, J.-P. Nonrandom fusion of L-plastin (LCP1) and LAZ3 (BCL6) genes by t(3,13)(q27,q14) chromosome translocation in two cases of B-cell non-Hodgkin lymphoma. Genes Chromosomes Cancer 26: 97-105, 1999. 3. Giometti, C. S., Anderson, N. L. A variant of human nonmuscle tropomyosin found in fibroblasts by using two-dimensional electrophoresis. J. Biol. Chem. 256: 11840-11846, 1981. -
说明
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Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- LCP1 (Lymphocyte Cytosolic Protein 1 (LCP1))
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别名
- LCP1
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背景
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Synonyms: Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1, LCP1, PLS2
Tissue Specificity: Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T-lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.
Background: Plastin-2 is a protein that in humans is encoded by the LCP1 gene. This gene is mapped to 13q14.13. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
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分子量
- 70 kDa
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基因ID
- 3936
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UniProt
- P13796
抗原
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