MIB1 抗体 (AA 465-732)
Quick Overview for MIB1 抗体 (AA 465-732) (ABIN6719398)
抗原
See all MIB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 465-732
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原理
- Anti-Mib1/Mindbomb Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Mib1/Mindbomb Antibody Picoband® (ABIN6719398). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Mib1 Mindbomb recombinant protein (Position: H465-E732).
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亚型
- IgG
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anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 6-221) antibody
MIB1 适用: 人, 猴 ELISA, WB, ICC, FACS 宿主: 小鼠 Monoclonal 6A9C9 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332) antibodyMIB1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 13-42), (N-Term) antibodyMIB1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4448 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 901-950) antibodyMIB1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 769-1000) antibodyMIB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 560-860) antibodyMIB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (C-Term) antibodyMIB1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (N-Term) antibodyMIB1 适用: Drosophila melanogaster ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Barsi, J. C., Rajendra, R., Wu, J. I., Artzt, K. Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech. Dev. 122: 1106-1117, 2005. 2. Henshall, D. C., Schindler, C. K., So, N. K., Lan, J.-Q., Meller, R., Simon, R. P.Death-associated protein kinase expression in human temporal lobe epilepsy. Ann. Neurol. 55: 485-494, 2004. 3. Jin, Y., Blue, E. K., Dixon, S., Shao, Z., Gallagher, P. J. A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK. J. Biol. Chem. 277: 46980-46986, 2002. -
说明
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Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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别名
- MIB1
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背景
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Synonyms: E3 ubiquitin-protein ligase MIB1, DAPK-interacting protein 1, DIP-1, Mind bomb homolog 1, RING-type E3 ubiquitin transferase MIB1 , Zinc finger ZZ type with ankyrin repeat domain protein 2, MIB1, DIP1, KIAA1323, ZZANK2
Tissue Specificity: Widely expressed at low level. Expressed at higher level in spinal cord, ovary, whole brain, and all specific brain regions examined.
Background: E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene. It is mapped to 18q11.2. This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
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分子量
- 110 kDa
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基因ID
- 57534
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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